Determination of the Newer Quinolones Levofloxacin and Moxifloxacin in Plasma by High-Performance Liquid Chromatography with Fluorescence Detection

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Determination of the newer quinolones levofloxacin and moxifloxacin in plasma by high-performance liquid chromatography with fluorescence detection.

A simple, accurate, sensitive, and precise reversed-phase (RP) high-performance liquid chromatographic (HPLC) method with fluorescence detection allowing the sensitive and specific quantitation of the newer fluoroquinolones levofloxacin and moxifloxacin is described. Moxifloxacin is used as the internal standard for the determination of levofloxacin and vice versa. A single-step liquid-liquid e...

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ژورنال

عنوان ژورنال: Journal of Chromatographic Science

سال: 2006

ISSN: 0021-9665,1945-239X

DOI: 10.1093/chromsci/44.4.205